Potential target genes of EMX2 include Odz/Ten-M and other gene families with implications for cortical patterning
H Li, KM Bishop, DDM O'Leary - Molecular and Cellular Neuroscience, 2006 - Elsevier
EMX2 and PAX6 are expressed by cortical progenitors and specify area patterning. We used
representational difference analysis (RDA) to compare expressed RNAs from wild type and
Emx2−/− cortex and identified 41 unique clones. Using secondary screening by in situ
hybridization, we selected five genes for further analysis, Cdk4, Cofilin1, Crmp1, ME2, and
Odz4, involved in neuronal proliferation, differentiation, migration, and axon guidance. Each
exhibits differential expression in wild type cortex. Odz4 is one of four members of a …
representational difference analysis (RDA) to compare expressed RNAs from wild type and
Emx2−/− cortex and identified 41 unique clones. Using secondary screening by in situ
hybridization, we selected five genes for further analysis, Cdk4, Cofilin1, Crmp1, ME2, and
Odz4, involved in neuronal proliferation, differentiation, migration, and axon guidance. Each
exhibits differential expression in wild type cortex. Odz4 is one of four members of a …
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